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A utility‐based design for randomized comparative trials with ordinal outcomes and prognostic subgroups

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Publication:4628384
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DOI10.1111/biom.12842zbMath1414.62462OpenAlexW2793259039WikidataQ48188540 ScholiaQ48188540MaRDI QIDQ4628384

Peter F. Thall, Wayne L. Hofstetter, Ying Yuan, Joan H. Elizondo, Thomas A. Murray

Publication date: 13 March 2019

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc6054910

zbMATH Keywords

hierarchical modelordinal responseprecision medicinenon-proportional oddsutility-based design


Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05)


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A multi-armed Bayesian ordinal outcome utility-based sequential trial with a pairwise null clustering prior, BAGS: A Bayesian Adaptive Group Sequential Trial Design With Subgroup-Specific Survival Comparisons



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