Stochastic Modelling of Multiple Random Genetic Mutations Under the Cancer Stem Cell Hypothesis

DOI10.1080/08898480.2012.725379zbMath1409.92215OpenAlexW2071097316MaRDI QIDQ4628522

Cristian Tomasetti

Publication date: 14 March 2019

Published in: Mathematical Population Studies (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/08898480.2012.725379

zbMATH Keywords

branching processestumor growthstem cellstumor heterogeneitygenetic mutations

Mathematics Subject Classification ID

Applications of branching processes (60J85) Population dynamics (general) (92D25) Developmental biology, pattern formation (92C15) Genetics and epigenetics (92D10)

Cites Work

• Unnamed Item
• Evolution of resistance and progression to disease during clonal expansion of cancer
• A stochastic model for the origin and treatment of tumors containing drug-resistant cells
• Waiting Time Models of Cancer Progression
• Biomechanical and Nutrient Controls in the Growth of Mammalian Cell Populations
• Population-size-dependent, age-structured branching processes linger around their carrying capacity
• Viability of Small Populations Experiencing Recurring Catastrophes

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