Optimal duration and dosage of BCG intravesical immunotherapy: A free final time optimal control approach

DOI10.1002/MMA.4745zbMath1390.92060OpenAlexW2790814079WikidataQ58195969 ScholiaQ58195969MaRDI QIDQ4644003

Ilias Elmouki, Meryem Alkama, Abdelilah Larrache, Mostafa Rachik

Publication date: 30 May 2018

Published in: Mathematical Methods in the Applied Sciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/mma.4745

zbMATH Keywords

optimal controlmaximum principlebladder cancerfree final timeBCG immunotherapyfinal gain function

Mathematics Subject Classification ID

Numerical methods based on necessary conditions (49M05) Dynamical systems in biology (37N25) Medical applications (general) (92C50) Existence theories for optimal control problems involving ordinary differential equations (49J15) Optimality conditions for problems involving ordinary differential equations (49K15)

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