Coupling systems biology with multiscale mechanics, for computer simulations of bone remodeling

DOI10.1016/j.cma.2012.10.015zbMath1297.74078OpenAlexW1983310455MaRDI QIDQ465736

Stefan Scheiner, Christian Hellmich, Peter Pivonka

Publication date: 24 October 2014

Published in: Computer Methods in Applied Mechanics and Engineering (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.cma.2012.10.015

zbMATH Keywords

mathematical modelingmechanobiologybone cell dynamicscontinuum micromechanics

Mathematics Subject Classification ID

Biomechanical solid mechanics (74L15) Systems biology, networks (92C42)

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Cites Work

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• Modelling the anabolic response of bone using a cell population model
• The structure of the linear anisotropic elastic symmetries
• External bone remodeling through boundary elements and damage mechanics
• Porous polycrystals built up by uniformly and axisymmetrically oriented needles: homogenization of elastic properties
• The determination of stress and strain concentrations at an ellipsoidal inclusion in an anisotropic material
• Continuum micromechanics
• Ductile sliding between mineral crystals followed by rupture of collagen crosslinks: experimentally supported micromechanical explanation of bone strength
• Theoretical investigation of the role of the RANK-RANKL-OPG system in bone remodeling
• Modeling the interactions between osteoblast and osteoclast activities in bone remodeling
• `Universal' microstructural patterns in cortical and trabecular, extracellular and extravascular bone materials: micromechanics-based prediction of anisotropic elasticity
• Continuum micro-mechanics of elastoplastic polycrystals
• Applied micromechanics of porous materials. Lecture Notes of a CISM course.
• Elastic properties of reinforced solids: Some theoretical principles
• Micro-macro numerical modelling of bone regeneration in tissue engineering
• The determination of the elastic field of an ellipsoidal inclusion, and related problems
• A combined fracture-micromechanics model for tensile strain-softening in brittle materials, based on propagation of interacting microcracks
• Some remarks on the compressed matrix representation of symmetric second-order and fourth-order tensors
• Multiscale modeling of elastic properties of cortical bone

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