Clinical Trial Designs Based on Sequential Conditional Probability Ratio Tests and Reverse Stochastic Curtailing

DOI10.2307/3109774zbMath1058.62659OpenAlexW2067448453WikidataQ74658572 ScholiaQ74658572MaRDI QIDQ4666003

Xiaoping Xiong, Michael H. Kutner, Ming Tan

Publication date: 11 April 2005

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.2307/3109774

zbMATH Keywords

conditional likelihoodmaximum likelihood ratio testWald SPRTmaximum informationinformation time fractionphase II and phase III trial

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical analysis (62L10)

Related Items (6)

Multistage Evaluation of Measurement Error in a Reliability Study ⋮ A nonparametric test for the evaluation of group sequential clinical trials with covariate information ⋮ Stopping rules for long-term clinical trials based on two consecutive rejections of the null hypothesis ⋮ Testing Secondary Hypotheses Following Sequential Clinical Trials ⋮ Sequential Conditional Probability Ratio Tests for Normalized Test Statistic on Information Time ⋮ STATISTICAL METHODS FOR MONITORING CLINICAL TRIALS

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