Testing Secondary Hypotheses Following Sequential Clinical Trials

DOI10.1111/j.0006-341X.2000.00640.xzbMath1060.62638WikidataQ73946399 ScholiaQ73946399MaRDI QIDQ4667496

Xiaoping Xiong, Ming Tan, Aiyi Liu, James M. Boyett

Publication date: 20 April 2005

Published in: Biometrics (Search for Journal in Brave)

zbMATH Keywords

sequential monitoringBrownian motion approximationWhitehead's model

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05) Testing in survival analysis and censored data (62N03)

Cites Work

• Unnamed Item
• Statistical approaches to interim monitoring of medical trials: A review and commentary
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• A Computationally Simpler Algorithm for the UMVUE of a Normal Mean Following a Group Sequential Trial
• The distribution of brownian motion on linear stopping boundaries
• Minimum variance unbiased estimation of the drift of brownian motion with linear stopping boundaries
• Clinical Trial Designs Based on Sequential Conditional Probability Ratio Tests and Reverse Stochastic Curtailing
• On the bias of maximum likelihood estimation following a sequential test
• Supplementary Analysis at the Conclusion of a Sequential Clinical Trial
• Information and information fractions for design and sequential monitoring of clinical trials

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