Step Contrasts for Identifying the Minimum Effective Dose

DOI10.1081/STA-200045872zbMath1062.62238MaRDI QIDQ4678794

Show-Li Jan

Publication date: 23 May 2005

Published in: Communications in Statistics - Theory and Methods (Search for Journal in Brave)

zbMATH Keywords

tablestoxicologyminimum effective dosedrug developmentdose-response studyHelmert contrastspairwise contrastsstep contrastsstep-down test

Mathematics Subject Classification ID

Nonparametric hypothesis testing (62G10) Applications of statistics to biology and medical sciences; meta analysis (62P10) Parametric hypothesis testing (62F03) Monte Carlo methods (65C05)

Uses Software

• SAS
• AS 195

Cites Work

• Algorithm AS 195: Multivariate Normal Probabilities with Error Bound
• Multiple Test Procedures for Dose Finding
• Some new multiple-test procedures for dose finding

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