Exact Permutational Tests for Group Sequential Clinical Trials

DOI10.2307/2533442zbMath0826.62061OpenAlexW2324444949WikidataQ52364591 ScholiaQ52364591MaRDI QIDQ4844281

Anastasios A. Tsiatis, Nitin R. Patel, Cyrus R. Mehta, Pralay Senchaudhuri

Publication date: 22 October 1995

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.2307/2533442

zbMATH Keywords

algorithmrandomizationstopping rulescategorical dataexact testsstopping boundariesearly stoppinglinear rank statisticsrepeated significance testsinterim monitoringO'Brien-Fleming boundarygroup sequential clinical trialssequential Wilcoxon testerror spending functionsexact boundary generating functionexact joint permutational distributionLan-DeMets procedure

Mathematics Subject Classification ID

Nonparametric hypothesis testing (62G10) Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical analysis (62L10) Probabilistic methods, stochastic differential equations (65C99)

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A Shift Algorithm for Exact Computation in Sequential Tests with Binary Outcome ⋮ Sequential Monitoring of Randomization Tests: Stratified Randomization ⋮ On the use ofR-estimators in analyzing repeated measures incomplete block clinical trials with baseline values as covariates ⋮ A discrete time sequential process for analyzing censored survival data using the likelihood ratio

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