Glucose-lactate metabolic cooperation in cancer: insights from a spatial mathematical model and implications for targeted therapy

DOI10.1016/j.jtbi.2014.09.018zbMath1303.92032OpenAlexW2128558411WikidataQ38952460 ScholiaQ38952460MaRDI QIDQ485684

Philip K. Maini, Natasha K. Martin, Jessica B. McGillen, Eamonn A. Gaffney, Catherine J. Kelly, Alicia Martínez-González, Víctor M. Pérez-García

Publication date: 13 January 2015

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2014.09.018

zbMATH Keywords

partial differential equationscancer metabolismmultidimensional sensitivity analysis

Mathematics Subject Classification ID

Medical applications (general) (92C50) Biochemistry, molecular biology (92C40)

Related Items (1)

Analysis of a model for tumor growth and lactate exchanges in a glioma

Uses Software

• ElemStatLearn

Cites Work

• Unnamed Item
• A mathematical model for the glucose-lactate metabolism of in vitro cancer cells
• Computational analysis of the influence of the microenvironment on carcinogenesis
• A methodology for performing global uncertainty and sensitivity analysis in systems biology
• A Compendium of Partial Differential Equation Models
• Random forests

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