Mathematical analysis of activation thresholds in enzyme-catalyzed positive feedbacks: application to the feedbacks of blood coagulation.

DOI10.1073/pnas.92.19.8744zbMath0832.92007OpenAlexW1992695863WikidataQ33923443 ScholiaQ33923443MaRDI QIDQ4856914

Edward Beltrami, Jolyon Jesty

Publication date: 5 March 1996

Published in: Proceedings of the National Academy of Sciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1073/pnas.92.19.8744

zbMATH Keywords

inhibitionoscillatory behaviorprotease inhibitorsinactivationproteolytic enzymesexcitation thresholdproteasesenzyme cascadeshierarchy of enzyme-catalyzed positive feedback loopskinetics of enzyme generationlong-range feedback

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Related Items (6)

Mathematical Models for Blood Coagulation ⋮ A Model Incorporating Some of the Mechanical and Biochemical Factors Underlying Clot Formation and Dissolution in Flowing Blood ⋮ Ultrasound detection of externally induced microthrombi cloud formation: a theoretical study ⋮ The role of membrane patch size and flow in regulating a proteolytic feedback threshold on a membrane: Possible application in blood coagulation ⋮ Instabilities in fibrinolytic regulatory system. Theoretical analysis of blow-up phenomena ⋮ Mathematical Modeling of Thrombin Generation and Wave Propagation: From Simple to Complex Models and Backwards

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