Testing for Gene–Environment and Gene–Gene Interactions Under Monotonicity Constraints

DOI10.1080/01621459.2012.726892zbMath1259.62098OpenAlexW2104709631MaRDI QIDQ4904722

Summer S. Han, Nilanjan Chatterjee, Philip S. Rosenberg

Publication date: 31 January 2013

Published in: Journal of the American Statistical Association (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/01621459.2012.726892

zbMATH Keywords

isotonic regressionorder restrictionsgene-environment interactionsgenome-wide association study (GWAS)constrained likelihood ratio test

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Parametric hypothesis testing (62F03) Parametric inference under constraints (62F30) Genetics and epigenetics (92D10)

Related Items (1)

An exposure-weighted score test for genetic associations integrating environmental risk factors

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