Semiparametric Dose Finding Methods for Partially Ordered Drug Combinations

DOI10.5705/ss.202020.0248OpenAlexW4200178593MaRDI QIDQ5041342

Nolan A. Wages, John O'Quigley, Matthieu Clertant

Publication date: 13 October 2022

Published in: Statistica Sinica (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.5705/ss.202020.0248

zbMATH Keywords

Bayesian methodpartial orderingsemiparametric methodphase I clinical trialsdose-finding design

Mathematics Subject Classification ID

Statistics (62-XX)

Cites Work

• The treatment versus experimentation dilemma in dose finding studies
• Continual Reassessment Method for Partial Ordering
• A Hierarchical Bayesian Design for Phase I Trials of Novel Combinations of Cancer Therapeutic Agents
• Dose-Finding with Two Agents in Phase I Oncology Trials
• Design and Analysis of Phase I Clinical Trials
• Coherence principles in dose-finding studies
• The role of minimal sets in dose finding studies
• Semiparametric Dose Finding Methods
• A Parallel Phase I/II Clinical Trial Design for Combination Therapies
• Two‐Dimensional Dose Finding in Discrete Dose Space