Two-stage phase II trials with early stopping for effectiveness and safety as well as ineffectiveness or harm

DOI10.1080/03610926.2017.1400054OpenAlexW2773797396MaRDI QIDQ5076974

Wanyi Chen, Shixin Li, Hua Jin

Publication date: 17 May 2022

Published in: Communications in Statistics - Theory and Methods (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/03610926.2017.1400054

zbMATH Keywords

optimal designphase II trialsearly stoppingtoxicityminimax design

Mathematics Subject Classification ID

Statistics (62-XX)

Cites Work

• Design and Analysis of Phase I Clinical Trials
• One-Sample Multiple Testing Procedure for Phase II Clinical Trials
• Designs for Phase II Trials Allowing for a Trade-Off between Response and Toxicity
• Incorporating Toxicity Considerations Into the Design of Two-Stage Phase II Clinical Trials
• Bivariate Sequential Designs for Phase II Trials

This page was built for publication: Two-stage phase II trials with early stopping for effectiveness and safety as well as ineffectiveness or harm