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Seamless phase II/III/IIIb clinical trial designs with different endpoints for different phases

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Publication:5078036
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DOI10.1080/03610926.2019.1618871OpenAlexW2947700554WikidataQ127782097 ScholiaQ127782097MaRDI QIDQ5078036

Tianyue Zhou, Peng-Liang Zhao, Xiao-Dong Luo, Hui Quan

Publication date: 20 May 2022

Published in: Communications in Statistics - Theory and Methods (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/03610926.2019.1618871


zbMATH Keywords

conditional powermultiplicity adjustmentcombination testestimation of treatment effect


Mathematics Subject Classification ID

Statistics (62-XX)





Cites Work

  • A sharper Bonferroni procedure for multiple tests of significance
  • Recursive Combination Tests
  • Modification of Sample Size in Group Sequential Clinical Trials
  • Confirmatory Seamless Phase II/III Clinical Trials with Hypotheses Selection at Interim: General Concepts




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