Uniform Asymptotic Expansions beyond the tQSSA for the Goldbeter--Koshland Switch
DOI10.1137/19M1254416zbMath1444.34063OpenAlexW3025945606MaRDI QIDQ5110574
Alessandro Borri, A. Milanesi, Pierluigi Vellucci, Giovanna Tomassetti, Alberto Maria Bersani
Publication date: 21 May 2020
Published in: SIAM Journal on Applied Mathematics (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1137/19m1254416
singular perturbationsasymptotic expansionscenter manifoldMichaelis-Menten kineticstotal quasi-steady state approximationcovalent modificationGoldbeter-Koshland switch
Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40) Qualitative investigation and simulation of ordinary differential equation models (34C60) Invariant manifolds for ordinary differential equations (34C45) Singular perturbations for ordinary differential equations (34E15) Asymptotic expansions of solutions to ordinary differential equations (34E05)
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