Sample Size Reassessment in Adaptive Clinical Trials Using a Bias Corrected Estimate

DOI10.1002/bimj.200390051zbMath1441.62313OpenAlexW2042641446MaRDI QIDQ5122412

Gernot Wassmer, Silke Coburger

Publication date: 22 September 2020

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/bimj.200390051

zbMATH Keywords

adaptive designspoint estimationearly stoppingsample size reassessmentgroup sequential test designs

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Related Items (1)

Sample size optimization and initial allocation of the significance levels in group sequential trials with multiple endpoints

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