Adaptive seamless clinical trials using early outcomes for treatment or subgroup selection: Methods, simulation model and their implementation in R

DOI10.1002/BIMJ.201900020zbMath1448.62161arXiv1901.08365OpenAlexW3009524190WikidataQ89968680 ScholiaQ89968680MaRDI QIDQ5135525

Tim Friede, Nigel Stallard, Nicholas Parsons

Publication date: 23 November 2020

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1901.08365

zbMATH Keywords

clinical trialsadaptive designclosed test procedurecombination testDunnett test

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Related Items (2)

New insights into adaptive enrichment designs ⋮ Improving adaptive seamless designs through Bayesian optimization

Uses Software

• asd
• Unnamed Item

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