An Optimizing Up-and-Down Design

DOI10.1007/978-1-4757-3419-5_19zbMath1423.62108OpenAlexW180701887MaRDI QIDQ5233891

Euloge E. Kpamegan, Nancy Flournoy

Publication date: 9 September 2019

Published in: Nonconvex Optimization and Its Applications (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/978-1-4757-3419-5_19

zbMATH Keywords

Markov chainsstochastic approximationstationary treatment distributionphase I/II clinical trialrandom walk designsconstant gain stochastic algorithm

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05) Optimal stopping in statistics (62L15)

Related Items (1)

Penalized optimal designs for dose-finding

Cites Work

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• Up-and-Down Designs for Selecting the Dose with Maximum Success Probability
• Asymptotic Distribution of Stochastic Approximation Procedures
• Some Results for Discrete Unimodality
• A Method for Obtaining and Analyzing Sensitivity Data
• First Passage and Recurrence Distributions
• Stochastic Estimation of the Maximum of a Regression Function
• On a Stochastic Approximation Method

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