Optimum designs for two treatments with unequal variances in the presence of covariates

DOI10.1093/biomet/asu071zbMath1452.62573OpenAlexW2167955544MaRDI QIDQ5258438

Anthony C. Atkinson

Publication date: 26 June 2015

Published in: Biometrika (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1093/biomet/asu071

zbMATH Keywords

D-optimalityrandomizationequivalence theoremclinical trialpersonalized medicinevariance heterogeneityNeyman allocation

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05)

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