Reduction of calcium release site models via fast/slow analysis and iterative aggregation/disaggregation

DOI10.1063/1.3223663zbMath1317.92026OpenAlexW2069730675WikidataQ44950789 ScholiaQ44950789MaRDI QIDQ5264315

Gregory D. Smith, Yan Hao, Peter Kemper

Publication date: 27 July 2015

Published in: Chaos: An Interdisciplinary Journal of Nonlinear Science (Search for Journal in Brave)

Full work available at URL: https://scholarworks.wm.edu/cgi/viewcontent.cgi?article=1007&context=appliedsciencepub

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Cell biology (92C37)

Related Items (2)

Particle-Based Multiscale Modeling of Calcium Puff Dynamics ⋮ Models of cardiac excitation-contraction coupling in ventricular myocytes

Cites Work

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• A stochastic automata network descriptor for Markov chain models of instantaneously coupled intracellular Ca\(^{2+}\) channels
• Superposition of spatially interacting aggregated continuous time Markov chains
• Calcium-dependent inactivation and the dynamics of calcium puffs and sparks
• Calcium release site ultrastructure and the dynamics of puffs and sparks
• Iterative Methods for Computing Stationary Distributions of Nearly Completely Decomposable Markov Chains
• Iterative aggregation/disaggregation techniques for nearly uncoupled markov chains

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