Shrunken p‐Values for Assessing Differential Expression with Applications to Genomic Data Analysis

DOI10.1111/j.1541-0420.2006.00616.xzbMath1114.62117OpenAlexW1994810683WikidataQ31083716 ScholiaQ31083716MaRDI QIDQ5295369

Debashis Ghosh

Publication date: 27 July 2007

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1111/j.1541-0420.2006.00616.x

zbMATH Keywords

multiple comparisonsshrinkage estimatorssimultaneous inferencemicroarraysJames-Stein estimators

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Statistical decision theory (62C99) Paired and multiple comparisons; multiple testing (62J15)

Related Items (2)

Estimating the Null Distribution to Adjust Observed Confidence Levels for Genome-Scale Screening ⋮ Shrinkage estimation of effect sizes as an alternative to hypothesis testing followed by estimation in high-dimensional biology: applications to differential gene expression

Uses Software

• SPADE

Cites Work

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• Error-Rate and Decision-Theoretic Methods of Multiple Testing: Which Genes Have High Objective Probabilities of Differential Expression?

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