Stochastic approximation with virtual observations for dose-finding on discrete levels

DOI10.1093/BIOMET/ASP065zbMath1183.62140OpenAlexW2024202679WikidataQ36142945 ScholiaQ36142945MaRDI QIDQ5305474

Ying-Kuen Cheung, Mitchell S. V. Elkind

Publication date: 22 March 2010

Published in: Biometrika (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc3412600

zbMATH Keywords

heteroscedasticityrobust estimationdichotomized datadiscrete barriercontinual re-assessment methodsemiparametric mean-variance relationship

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50) Stochastic approximation (62L20) Estimation in survival analysis and censored data (62N02)

Related Items (7)

Stochastic approximation with series of delayed observations ⋮ Stochastic approximation and modern model-based designs for dose-finding clinical trials ⋮ Continual reassessment and related dose-finding designs ⋮ Stochastic approximation and compound delayed observations with independent random time delay distribution ⋮ Adaptive clinical trial designs for phase I cancer studies ⋮ Continual reassessment method with multiple toxicity constraints ⋮ Multivariate Markov models for the conditional probability of toxicity in phase II trials

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