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Retroactivity Attenuation in Bio-Molecular Systems Based on Timescale Separation

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Publication:5347665
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DOI10.1109/TAC.2010.2069631zbMath1368.93399MaRDI QIDQ5347665

Domitilla Del Vecchio, Shridhar Jayanthi

Publication date: 25 August 2017

Published in: IEEE Transactions on Automatic Control (Search for Journal in Brave)



Mathematics Subject Classification ID

Time-scale analysis and singular perturbations in control/observation systems (93C70) Biochemistry, molecular biology (92C40) Singular perturbations for ordinary differential equations (34E15) Dynamic equations on time scales or measure chains (34N05)


Related Items (6)

Optimizing enzymatic catalysts for rapid turnover of substrates with low enzyme sequestration ⋮ Structural analysis in biology: a control-theoretic approach ⋮ Physically-plausible modelling of biomolecular systems: a simplified, energy-based model of the mitochondrial electron transport chain ⋮ Layered decomposition for the model order reduction of timescale separated biochemical reaction networks ⋮ Singularly perturbed problems with multi-tempo fast variables ⋮ The inverse correlation between robustness and sensitivity to autoregulation in two-component systems






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