A Unified Family of Covariate-Adjusted Response-Adaptive Designs Based on Efficiency and Ethics

DOI10.1080/01621459.2014.903846zbMath1373.62382OpenAlexW2076281653WikidataQ30977270 ScholiaQ30977270MaRDI QIDQ5367369

Jianhua Hu, Hongjian Zhu, Fei-fang Hu

Publication date: 13 October 2017

Published in: Journal of the American Statistical Association (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc4478080

zbMATH Keywords

asymptotic propertiesrandomizationpowerclinical trialgeneralized linear modelspersonalized medicinecovariate-adjusted response-adaptive (CARA) designs

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Applications of statistics to social sciences (62P25) Generalized linear models (logistic models) (62J12) Response surface designs (62K20)

Related Items (6)

Generalized Efron's biased coin design and its theoretical properties ⋮ Covariate-adaptive designs with missing covariates in clinical trials ⋮ Dynamic Causal Effects Evaluation in A/B Testing with a Reinforcement Learning Framework ⋮ A general characterization of optimal tie-breaker designs ⋮ Response-adaptive randomization in clinical trials: from myths to practical considerations ⋮ Nonparametric covariate-adjusted response-adaptive design based on a functional urn model

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