The treatment versus experimentation dilemma in dose finding studies
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Publication:538132
DOI10.1016/j.jspi.2011.03.001zbMath1213.62167OpenAlexW1970342933MaRDI QIDQ538132
Yosef Rinott, Micha Mandel, David Azriel
Publication date: 23 May 2011
Published in: Journal of Statistical Planning and Inference (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1016/j.jspi.2011.03.001
Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05) Medical applications (general) (92C50)
Related Items (14)
A note on continual reassessment method ⋮ Optimal sequential designs in phase I studies ⋮ Semiparametric Dose Finding Methods for Partially Ordered Drug Combinations ⋮ Response adaptive designs for phase II trials with binary endpoint based on context-dependent information measures ⋮ The role of minimal sets in dose finding studies ⋮ Optimal designs for contingent response models with application to toxicity-efficacy studies ⋮ Information in a two-stage adaptive optimal design ⋮ Performance Measures in Dose‐Finding Experiments ⋮ A continual reassessment method without undue risk of toxicity ⋮ A note on the robustness of the continual reassessment method ⋮ Adaptive clinical trial designs for phase I cancer studies ⋮ Adaptive Designs to Maximize Power in Clinical Trials with Multiple Treatments ⋮ Using Joint Utilities of the Times to Response and Toxicity to Adaptively Optimize Schedule–Dose Regimes ⋮ A conversation with Nancy Flournoy
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- Non-Parametric Up-and-down Experimentation
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- A Curve‐Free Method for Phase I Clinical Trials
- A Method for Obtaining and Analyzing Sensitivity Data
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