Design of the lac gene circuit revisited

DOI10.1016/j.mbs.2011.03.008zbMath1214.92026OpenAlexW2053291786WikidataQ35076513 ScholiaQ35076513MaRDI QIDQ541855

Michael A. Savageau

Publication date: 8 June 2011

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc3126112

zbMATH Keywords

biochemical systems analysisbiological design principlesgene circuitrypower-law formalismsystem design space

Mathematics Subject Classification ID

Dynamical systems in biology (37N25) Biochemistry, molecular biology (92C40) General theory for ordinary differential equations (34A99) Systems biology, networks (92C42)

Related Items (4)

Biochemical systems theory: a review ⋮ Chemical reaction network approaches to biochemical systems theory ⋮ Phenotypic deconstruction of gene circuitry ⋮ Kinetic approaches to lactose operon induction and bimodality

Cites Work

• Bistability of the lac operon during growth of Escherichia coli on lactose and lactose + glucose
• Alternative designs for a genetic switch: Analysis of switching times using the piecewise power-law representation
• Design principles for elementary gene circuits: Elements, methods, and examples
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