Summarizing EC50 estimates from multiple dose‐response experiments: A comparison of a meta‐analysis strategy to a mixed‐effects model approach

DOI10.1002/bimj.201300123zbMath1441.62388OpenAlexW1929871029WikidataQ42807351 ScholiaQ42807351MaRDI QIDQ5420234

Xiaoqi Jiang, Annette Kopp-Schneider

Publication date: 11 June 2014

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/bimj.201300123

zbMATH Keywords

meta-analysisnonlinear mixed-effects modeldose-response analysislog-logistic modelEC50 estimate

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Analysis of variance and covariance (ANOVA) (62J10)

Uses Software

• metafor

Cites Work

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• Seemingly unrelated nonlinear regressions
• Nonlinear Regression with Autocorrelated Errors
• Mixed-Effects Models in S and S-PLUS
• Analysis of binary data from a multicentre clinical trial
• Maximum Likelihood Computations with Repeated Measures: Application of the EM Algorithm
• Parametric Empirical Bayes Inference: Theory and Applications
• An Alternative Method for Meta-Analysis
• Simple Heterogeneity Variance Estimation for Meta-Analysis

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