Bayesian methods to overcome the winner's curse in genetic studies

DOI10.1214/10-AOAS373zbMath1220.62027arXiv0907.2770OpenAlexW3104135133MaRDI QIDQ542467

Lizhen Xu, Lei Sun, Radu V. Craiu

Publication date: 10 June 2011

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/0907.2770

zbMATH Keywords

Bayesian model averagingassociation studyhierarchical Bayes modelspike-and-slab prior

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Point estimation (62F10) Bayesian inference (62F15) Genetics and epigenetics (92D10)

Related Items (2)

The significance filter, the winner's curse and the need to shrink ⋮ A Bayesian model averaging approach for observational gene expression studies

Uses Software

• tsbridge

Cites Work

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• Bayesian model averaging: A tutorial. (with comments and a rejoinder).
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• Multiple comparisons distortions of parameter estimates
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• The Calculation of Posterior Distributions by Data Augmentation
• Bayesian Variable Selection in Linear Regression
• Prediction Via Orthogonalized Model Mixing
• Bayesian variable selection with related predictors
• Simulating normalizing constants: From importance sampling to bridge sampling to path sampling

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