Quasi steady-state approximations in complex intracellular signal transduction networks - a word of caution
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Publication:551897
DOI10.1007/s10910-007-9248-4zbMath1217.92052OpenAlexW2027571621MaRDI QIDQ551897
Morten Gram Pedersen, Alberto Maria Bersani, Enrico Bersani
Publication date: 21 July 2011
Published in: Journal of Mathematical Chemistry (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1007/s10910-007-9248-4
Michaelis-Menten kineticsdouble phosphorylationenzyme signaling networksMAPK cascadequasi steady-state assumption
Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Systems biology, networks (92C42)
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Cites Work
- Michaelis-Menten kinetics at high enzyme concentrations
- Enzyme kinetics for a two-step enzymic reaction with comparable initial enzyme-substrate ratios
- Time-dependent closed form solutions for fully competitive enzyme reactions
- Extending the quasi-steady state approximation by changing variables
- The Quasi-Steady-State Assumption: A Case Study in Perturbation
