Breaking the winner's curse in Mendelian randomization: rerandomized inverse variance weighted estimator

DOI10.1214/22-AOS2247arXiv2302.10470MaRDI QIDQ6046309

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Publication date: 10 May 2023

Published in: The Annals of Statistics (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/2302.10470

zbMATH Keywords

instrumental variablecausal inferencepost-selection inferenceinverse variance weightingtwo-sample Mendelian randomization

Mathematics Subject Classification ID

Asymptotic distribution theory in statistics (62E20) Applications of statistics to biology and medical sciences; meta analysis (62P10) Applications of statistics to social sciences (62P25) Point estimation (62F10)

Cites Work

• Statistical inference in two-sample summary-data Mendelian randomization using robust adjusted profile score
• Sparse linear models and \(l_1\)-regularized 2SLS with high-dimensional endogenous regressors and instruments
• Debiased inverse-variance weighted estimator in two-sample summary-data Mendelian randomization
• Instrumental variables estimation with many weak instruments using regularized JIVE
• INFERENCE IN INSTRUMENTAL VARIABLE MODELS WITH HETEROSKEDASTICITY AND MANY INSTRUMENTS
• Inference with Many Weak Instruments
• Consistent Estimation with a Large Number of Weak Instruments
• Conditional Expectation and Unbiased Sequential Estimation

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