A minimal mathematical model to study insulin synthesis and secretion process

DOI10.1016/J.APM.2023.06.012zbMath1525.92022MaRDI QIDQ6048924

Jayendrajyoti Kundu, Abhijit Paul, Samrat Chatterjee

Publication date: 13 October 2023

Published in: Applied Mathematical Modelling (Search for Journal in Brave)

zbMATH Keywords

insulintype 2 diabetesinsulin granule dynamicsglucose-stimulated insulin secretioninsulin synthesisinsulinoma

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Biochemistry, molecular biology (92C40)

Cites Work

• A methodology for performing global uncertainty and sensitivity analysis in systems biology
• A minimal model of glucose-stimulated insulin secretion process explores factors responsible for the development of type 2 diabetes
• Sensitivity and Uncertainty Analysis of Complex Models of Disease Transmission: An HIV Model, as an Example
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