Interplay of p53 and XIAP protein dynamics orchestrates cell fate in response to chemotherapy

DOI10.1016/J.JTBI.2023.111562zbMath1521.92056MaRDI QIDQ6053977

Roba Abukwaik, Fabian Spill, Elias Vera-Sigüenza, Daniel A. Tennant

Publication date: 27 September 2023

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

zbMATH Keywords

dynamical systemsapoptosismathematical biologycell signallingp53chemotherapy resistancecaspase-3XIAP

Mathematics Subject Classification ID

Medical applications (general) (92C50) Linear ordinary differential equations and systems (34A30)

Cites Work

• Decision making of the p53 network: death by integration
• The role of time delays in P53 gene regulatory network stimulated by growth factor

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