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Robust group sequential designs for trials with survival endpoints and delayed response

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Publication:6068473
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DOI10.1002/bimj.202000169zbMath1523.62119OpenAlexW4200375850MaRDI QIDQ6068473

Robin Ristl, Unnamed Author, Heiko Götte, Christopher Jennison, Martin Posch, Franz König, Cyrus R. Mehta, Pranab Ghosh

Publication date: 15 December 2023

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://purehost.bath.ac.uk/ws/files/253332939/Delayed_Response_Paper_2020_05_31.pdf


zbMATH Keywords

group sequential designlog-rank testnonproportional hazardsdelayed responseimmuno-oncologycancer immunologyFleming-Harrington testlate separation of survival curvesmax-combo testmodestly weighted log-rank test


Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)




Cites Work

  • Unnamed Item
  • On the versatility of the combination of the weighted log-rank statistics
  • Discrete Sequential Boundaries for Clinical Trials
  • A class of hypothesis tests for one and two sample censored survival data
  • Repeated Significance Testing for a General Class of Statistics Used in Censored Survival Analysis




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