Bayesian two‐stage sequential enrichment design for biomarker‐guided phase II trials for anticancer therapies

DOI10.1002/BIMJ.202100297zbMath1523.62213MaRDI QIDQ6068829

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Publication date: 15 December 2023

Published in: Biometrical Journal (Search for Journal in Brave)

zbMATH Keywords

Bayesian hierarchical modeltargeted therapyphase II clinical trialenrichment designborrow information

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

• A predictive enrichment procedure to identify potential responders to a new therapy for randomized, comparative controlled clinical studies
• Bayesian hierarchical classification and information sharing for clinical trials with subgroups and binary outcomes

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