Causal Inference in Transcriptome-Wide Association Studies with Invalid Instruments and GWAS Summary Data

DOI10.1080/01621459.2023.2183127OpenAlexW4321492198MaRDI QIDQ6077539

Xiaotong Shen, Unnamed Author, Unnamed Author

Publication date: 18 October 2023

Published in: Journal of the American Statistical Association (Search for Journal in Brave)

Full work available at URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557939

zbMATH Keywords

causal inferenceSNP2SLSgenome-wide association studiesMendelian randomization (MR)reference paneltruncated \(L_1\)-constraint (TLC)

Mathematics Subject Classification ID

Statistics (62-XX)

Cites Work

• Confidence Intervals for Causal Effects with Invalid Instruments using Two-Stage Hard Thresholding with Voting
• Statistical inference in two-sample summary-data Mendelian randomization using robust adjusted profile score
• On constrained and regularized high-dimensional regression
• Robust inference for the two-sample 2SLS estimator
• Approximating by the Wishart distribution
• A symmetric matrix-variate normal local approximation for the Wishart distribution and some applications
• Genomic Control for Association Studies
• Likelihood-Based Selection and Sharp Parameter Estimation
• On the Use of the Lasso for Instrumental Variables Estimation with Some Invalid Instruments
• Regularization Methods for High-Dimensional Instrumental Variables Regression With an Application to Genetical Genomics
• Weak‐instrument robust tests in two‐sample summary‐data Mendelian randomization

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