Modeling the development of cellular exhaustion and tumor-immune stalemate

DOI10.1007/S11538-023-01207-7zbMath1526.92016MaRDI QIDQ6078305

Doron Levy, Tyler Simmons

Publication date: 24 October 2023

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

zbMATH Keywords

immunotherapystalematecellular exhaustionprogenitor exhaustedterminally exhausted

Mathematics Subject Classification ID

Cell biology (92C37) Pathology, pathophysiology (92C32)

Cites Work

• Functional switching and stability of regulatory T cells
• Mathematical models for immunology: current state of the art and future research directions
• A theory of immunodominance and adaptive regulation
• Emergent group dynamics governed by regulatory cells produce a robust primary T cell response
• A mathematical model of cell-mediated immune response to tumor
• Quantitative immunology for physicists
• Interactions between the immune system and cancer: A brief review of non-spatial mathematical models
• Mathematical models of immune effector responses to viral infections: Virus control versus the development of pathology
• Modeling LSD1-mediated tumor stagnation
• Basic Principles in Modeling Adaptive Regulation and Immunodominance

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