Statistical inference of the rates of cell proliferation and phenotypic switching in cancer

DOI10.1016/j.jtbi.2023.111497zbMath1518.92042arXiv2306.08096MaRDI QIDQ6174231

Kevin Leder, Jasmine Foo, Einar Bjarki Gunnarsson

Publication date: 14 July 2023

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/2306.08096

zbMATH Keywords

maximum likelihood estimationmathematical modelingphenotypic switchingparameter identifiabilityepigeneticscancer evolution

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Developmental biology, pattern formation (92C15) Pathology, pathophysiology (92C32)

Cites Work

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• Relative frequencies in multitype branching processes
• A robust and efficient algorithm to find profile likelihood confidence intervals
• Understanding the role of phenotypic switching in cancer drug resistance
• Branching Process Models of Cancer
• Identification in Parametric Models

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