Dynamics of cell-type transition mediated by epigenetic modifications

DOI10.1016/J.JTBI.2023.111664zbMath1530.92017arXiv2309.07356OpenAlexW4388718771MaRDI QIDQ6177288

Qiaojun Situ, Jinzhi Lei, Rongsheng Huang

Publication date: 17 January 2024

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/2309.07356

zbMATH Keywords

multi-scale modelstem cell differentiationcell reprogrammingepigenetic stateWaddington landscape

Mathematics Subject Classification ID

Developmental biology, pattern formation (92C15) Cell biology (92C37) Systems biology, networks (92C42)

Cites Work

• Oscillations in cyclical neutropenia: new evidence based on mathematical modeling
• Evolutionary dynamics of cancer: from epigenetic regulation to cell population dynamics -- mathematical model framework, applications, and open problems
• A general mathematical framework for understanding the behavior of heterogeneous stem cell regeneration
• Cell-type switches induced by stochastic histone modification inheritance
• Mathematical model of adult stem cell regeneration with cross-talk between genetic and epigenetic regulation
• A delay model for noise-induced bi-directional switching

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