IL-27 in combination with anti-PD-1 can be anti-cancer or pro-cancer

DOI10.1016/J.JTBI.2023.111704zbMath1530.92091OpenAlexW4389776065MaRDI QIDQ6177320

Xue-Feng Bai, Avner Friedman, Kang-Ling Liao

Publication date: 17 January 2024

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2023.111704

zbMATH Keywords

combination therapyimmune checkpoint inhibitorsanti-PD-1interleukin-27

Mathematics Subject Classification ID

PDEs in connection with biology, chemistry and other natural sciences (35Q92) Medical applications (general) (92C50)

Cites Work

• The role of exosomes in pancreatic cancer microenvironment
• A mathematical model of tumor-immune interactions
• A methodology for performing global uncertainty and sensitivity analysis in systems biology
• Mathematical modeling of cancer treatment with radiation and PD-L1 inhibitor
• Mathematical model of sarcoidosis
• Modelling the interactions between tumour cells and a blood vessel in a microenvironment within a vascular tumour

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