Empirical quantification of predictive uncertainty due to model discrepancy by training with an ensemble of experimental designs: an application to ion channel kinetics

DOI10.1007/s11538-023-01224-6zbMath1530.92079arXiv2302.02942MaRDI QIDQ6188373

Chon Lok Lei, Gary R. Mirams, Simon P. Preston, Joseph G. Shuttleworth, Adam P. Hill, Monique J. Windley, Dominic G. Whittaker

Publication date: 11 January 2024

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/2302.02942

zbMATH Keywords

discrepancymathematical modelmisspecificationuncertainty quantificationexperimental designion channel

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Mathematical modeling or simulation for problems pertaining to biology (92-10) Experimental work for problems pertaining to biology (92-05)

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