A Bayesian method for estimating gene‐level polygenicity under the framework of transcriptome‐wide association study

DOI10.1002/SIM.9892arXiv2207.12173OpenAlexW4386244992MaRDI QIDQ6189843

Arunabha Majumdar, Bogdan Pasaniuc

Publication date: 4 March 2024

Published in: Statistics in Medicine (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/2207.12173

zbMATH Keywords

MCMChierarchical modelsspike and slab priorcomplex trait genomicsgene-level association

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

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• Bayesian variable selection regression for genome-wide association studies and other large-scale problems
• The positive false discovery rate: A Bayesian interpretation and the \(q\)-value
• Bayesian estimation of sparse signals with a continuous spike-and-slab prior
• Spike and slab variable selection: frequentist and Bayesian strategies
• Regularization and Variable Selection Via the Elastic Net

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