Simplification of a complex signal transduction model using invariants and flow equivalent servers

DOI10.1016/j.tcs.2011.06.013zbMath1230.92020OpenAlexW1989546403WikidataQ57700081 ScholiaQ57700081MaRDI QIDQ652148

Simona Pavan, Massimiliano De Pierro, Gianfranco Balbo, Daniele Manini, Andrea Picco, Andrea Veglio, Matteo Sereno, Francesca Cordero, Lucia Napione, Federico Bussolino, Andras Horvath

Publication date: 19 December 2011

Published in: Theoretical Computer Science (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.tcs.2011.06.013

zbMATH Keywords

angiogenesisPetri netssystems biologymodel simplification

Mathematics Subject Classification ID

Medical applications (general) (92C50) Models and methods for concurrent and distributed computing (process algebras, bisimulation, transition nets, etc.) (68Q85) Systems biology, networks (92C42)

Related Items (2)

Product Form Approximation of Transient Probabilities in Stochastic Reaction Networks ⋮ Approximate analysis of biological systems by hybrid switching jump diffusion

Uses Software

• GreatSPN
• Meddly

Cites Work

• Michaelis-Menten kinetics at high enzyme concentrations
• Recent developments in parameter estimation and structure identification of biochemical and genomic systems
• Parametric Analysis of Queuing Networks
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