A mathematical model for optimal functional disruption of biochemical networks

DOI10.1007/s10852-009-9118-0zbMath1229.92035OpenAlexW2075836947MaRDI QIDQ655173

Guglielmo Lulli, Enza Messina, Stefano Lanzeni, Francesco Archetti

Publication date: 2 January 2012

Published in: JMMA. Journal of Mathematical Modelling and Algorithms (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s10852-009-9118-0

zbMATH Keywords

mathematical modelingbi-level programmingdrug design

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Cell biology (92C37)

Related Items (1)

The stochastic interdiction median problem with disruption intensity levels

Uses Software

• Optknock

Cites Work

• Unnamed Item
• Unnamed Item
• Unnamed Item
• Graph models and mathematical programming in biochemical network analysis and metabolic engineering design
• Practical bilevel optimization. Algorithms and applications
• Foundations of bilevel programming
• Discrete linear bilevel programming problem
• A Representation and Economic Interpretation of a Two-Level Programming Problem
• The Mixed Integer Linear Bilevel Programming Problem

This page was built for publication: A mathematical model for optimal functional disruption of biochemical networks