Mathematical model for IL-2-based cancer immunotherapy

DOI10.1016/j.mbs.2024.109187zbMath1545.92052MaRDI QIDQ6566666

Jianjun Paul Tian, Tuan Anh Phan, John C. Dallon, Megan Dixon

Publication date: 3 July 2024

Published in: Mathematical Biosciences (Search for Journal in Brave)

zbMATH Keywords

immunotherapyIL-2\(\mathrm{CD}4^+\) T cell\(\mathrm{CD}8^+\) T cell

Mathematics Subject Classification ID

Medical applications (general) (92C50) Global stability of solutions to ordinary differential equations (34D23) Numerical bifurcation problems (65P30)

Cites Work

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• Mixed immunotherapy and chemotherapy of tumors: modeling, applications and biological interpretations
• A mathematical model of combined \textit{bacillus Calmette-Guerin} (BCG) and interleukin (IL)-2 immunotherapy of superficial bladder cancer
• Hopf bifurcation without parameters in deterministic and stochastic modeling of cancer virotherapy. I
• Stochastic dynamics of human papillomavirus delineates cervical cancer progression
• A stochastic framework for evaluating CAR T cell therapy efficacy and variability

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