A stochastic programming approach to the antibiotics time machine problem

DOI10.1016/J.MBS.2024.109191zbMATH Open1545.92064MaRDI QIDQ6566673

Burak Kocuk, Ali Rana Atilgan, Oğuz Mesüm

Publication date: 3 July 2024

Published in: Mathematical Biosciences (Search for Journal in Brave)

zbMATH Keywords

dynamic programmingfitness landscapemixed-integer linear programmingdrug deliverybacterial growth ratebeta-lactamase

Mathematics Subject Classification ID

Problems related to evolution (92D15) Mixed integer programming (90C11) Linear programming (90C05) Stochastic programming (90C15) Dynamic programming (90C39) Microbiology (92C70)

Cites Work

• A simple stochastic gene substitution model
• The sample average approximation method for stochastic discrete optimization
• Lectures on stochastic programming. Modeling and theory.
• Introduction to Stochastic Programming
• Antibiotics Time Machines Are Hard to Build
• Rational Design of Antibiotic Treatment Plans: A Treatment Strategy for Managing Evolution and Reversing Resistance
• Optimization problems involving matrix multiplication with applications in materials science and biology

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