Response-adaptive randomization for multiarm clinical trials using context-dependent information measures

DOI10.1002/bimj.202200301zbMATH Open1544.62334MaRDI QIDQ6595096

Ksenia Kasianova, Pavel Mozgunov, M. Ya. Kel'bert

Publication date: 29 August 2024

Published in: Biometrical Journal (Search for Journal in Brave)

zbMATH Keywords

experimental designinformation gainphase II clinical trialweighted information

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

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• Response adaptive designs for phase II trials with binary endpoint based on context-dependent information measures
• Response‐adaptive randomization for multi‐arm clinical trials using the forward looking Gittins index rule
• Adaptive designs for subpopulation analysis optimizing utility functions
• Information Theory and Statistical Mechanics
• An Information Theoretic Approach for Selecting Arms in Clinical Trials
• Covariate-adjusted response-adaptive designs based on semiparametric approaches
• An information theoretic phase I--II design for molecularly targeted agents that does not require an assumption of monotonicity

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