Incorporation of healthy volunteers data on receptor occupancy into a phase II proof-of-concept trial using a Bayesian dynamic borrowing design

DOI10.1002/bimj.202200305zbMath1544.62326MaRDI QIDQ6595102

Mauro Gasparini, Gaelle Saint-Hilary, Stephanie Galtier, Fulvio Di Stefano, Sandrine Guilleminot, Christelle Rodrigues, Veronique Robert

Publication date: 29 August 2024

Published in: Biometrical Journal (Search for Journal in Brave)

zbMATH Keywords

Bayesianhistorical databorrowingreceptor occupancyphase IIearly phasephysiology-based pharmacokinetics

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

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