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Optimal biased coins for two-arm clinical trials

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Publication:660035
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DOI10.4310/SII.2008.V1.N1.A11zbMath1230.62097MaRDI QIDQ660035

Jianhua Hu, Thomas E. Gwise, Fei-fang Hu

Publication date: 25 January 2012

Published in: Statistics and Its Interface (Search for Journal in Brave)


zbMATH Keywords

adaptive designcontinuous responsesbinary responses\(D\)-optimal biased coin, \(D_A\)-optimal biased coinresponse adaptive design


Mathematics Subject Classification ID

Optimal statistical designs (62K05) Medical applications (general) (92C50)


Related Items (6)

Efficient randomized-adaptive designs ⋮ An optimal response adaptive biased coin design with \(k\) heteroscedastic treatments ⋮ Sequential monitoring of response-adaptive randomized clinical trials ⋮ Implementing optimal allocation in clinical trials with multiple endpoints ⋮ Interim analysis of clinical trials based on urn models ⋮ Selecting a biased-coin design







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