Assessing efficacy in non-inferiority trials with non-adherence to interventions: are intention-to-treat and per-protocol analyses fit for purpose?

DOI10.1002/sim.10067zbMATH Open1546.62195MaRDI QIDQ6615873

Katherine Fielding, James Carpenter, Diana Elbourne, Jennifer A. Thompson, Elizabeth J. Williamson, Matthew Dodd

Publication date: 8 October 2024

Published in: Statistics in Medicine (Search for Journal in Brave)

zbMATH Keywords

compliancenon-inferiorityintention-to-treattrialadherenceper-protocol

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

• Unnamed Item
• Identification of causal effects on binary outcomes using structural mean models
• Using simulation studies to evaluate statistical methods

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