Design and sample size determination for multiple-dose randomized phase II trials for dose optimization

DOI10.1002/sim.10093zbMATH Open1546.62867MaRDI QIDQ6615956

Daniel Yang Li, Peng Yang, Bo Huang, Ruitao Lin, Ying Yuan

Publication date: 8 October 2024

Published in: Statistics in Medicine (Search for Journal in Brave)

zbMATH Keywords

randomized clinical trialdose findingrisk-benefit assessmentdose optimizationProject Optimus

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

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• A Two-Stage Design for Choosing among Several Experimental Treatments and a Control in Clinical Trials
• A Multiple Comparison Procedure for Comparing Several Treatments with a Control
• Two-stage selection and testing designs for comparative clinical trials
• DROID: dose-ranging approach to optimizing dose in oncology drug development

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